The price of Ethereum may be hampered by sales pressure, but the leading network continues to be heavily used by developers and users. After strong interaction from attendees, the blockchain giant once again became the leader in decentralized financial lending (DeFi).
DeFi loans are still the most profitable on the Ethereum network
A recent report highlighted Ethereum’s growing dominance in the blockchain sector. The network is solidifying its position as a financial foundation for decentralized finance lending, and the data is starting to present a compelling picture.
A look at data shared by Leon Waidmannmarket expert and head of research at the On-Chain Foundation, shows that ETH is now the revenue center of DeFi lending. This implies that most revenue flows through the ETH ecosystem, outpacing other major chains like Base, Plasma, and Arbitrum.
From borrowing fees to interest paid by active users, the EPF network continues to be the key level of settlement where value is constantly created. ETH is the center of revenue and describes network usage in addition to its continued dominance as the fundamental infrastructure behind DeFi’s most lucrative lending business.

As the chart shows, the Ethereum mainnet has consistently secured over 80-90% of all DeFi revenue and lending activity, further cementing its growing role in the financial landscape. Interestingly, this share has remained a dominant force even with the vigorous expansion of the Layer 2 and alt-Layer 1 channels.
The data shows that usage may be fragmented, but fees are not. Meanwhile, at the protocol level, Waidmann emphasized that the focus is much stronger. Amid this surge in DeFi revenue lending, Aave is the primary revenue driver in the market. Ethereum mainnetattracting more than 50% of total loan funds.
This part of the network was also responsible for over 60% of all active loans on ETH. Ultimately, the project generated approximately $885 million in fees in 2025 alone, reflecting the significant use of the network.
While the Ethereum mainnet secures balance sheets and profits, layers 2 optimize execution and user experience (UX). Waidmann noted that where trust and liquidity are greatest, Challenge credit markets are converging. “Ethereum Mainnet is not disrupted, but is strengthened,” the expert added.
Active ETH addresses targeting its peak
Another example of solid engagement on the Ethereum network is the increase in the number of active wallet addresses. Joseph Young, a crypto enthusiast, previously highlighted as active users on the network approach their record level. Such an increase in the number of active addresses suggests a renewed interest and conviction among the largest and individual investors.
At the time of publication, approximately 2.4 million wallet addresses were actively interacting with the network each week. This is an indication that tokenization, stable coinsand privacy infrastructures are all converging on Ethereum. Currently, Young said that ETH dominates the big three metas, while expressing his conviction about the network’s prospects.
Featured image of Adobe Stock, chart from Tradingview.com
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